Research Article
Study on the Hemostatic Effect of Semen Vaccariae Before and After Charcoal Preparation
Yaosheng Zhang,
Zeqiang Liu,
Jia Liu*,
Guohong Zhou*
Issue:
Volume 8, Issue 1, March 2024
Pages:
1-6
Received:
3 February 2024
Accepted:
26 February 2024
Published:
19 March 2024
DOI:
10.11648/j.ijcm.20240801.11
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Abstract: Aims: This study is aimed to verify the records in ancient Chinese classics that semen vaccariae was mainly used for traumatic hemorrhage caused by metal sharp weapons but need to be burned into ash first. Methods: The bleeding time and clotting time of tail-amputated bleeding experiment and capillary coagulation experiment of mice were measured to evaluate the hemostatic effect of semen vaccariae before and after charcoal preparation. Results: While semen vaccariae was used topically to mice, the bleeding time of charcoal group was significantly shortened (P < 0.05), but there was no significant difference in raw group. While semen vaccariae was used orally to mice, the bleeding time and clotting time in the low and high dose groups of raw groups decreased significantly (P < 0.05 or 0.01). In addition, the bleeding time in the high dose of raw group also decreased significantly (P < 0.05). However, animal death and animal weight loss were found in the raw group during the experiment. The clotting time was also decreased significantly in low, middle and high dose charcoal groups (P < 0.05 or 0.01). Conclusions: Semen vaccariae used topically after charcoal preparation has hemostatic effect, while semen vaccariae used orally both before and after charcoal preparation shows hemostatic effect, but raw semen vaccariae used orally has potential risk. This study to some extent verifies the records in ancient Chinese classics.
Abstract: Aims: This study is aimed to verify the records in ancient Chinese classics that semen vaccariae was mainly used for traumatic hemorrhage caused by metal sharp weapons but need to be burned into ash first. Methods: The bleeding time and clotting time of tail-amputated bleeding experiment and capillary coagulation experiment of mice were measured to...
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Research Article
Correlation Between Ultrasound Manifestations and Traditional Chinese Medicine Syndrome Differentiation of Breast Nodules
Issue:
Volume 8, Issue 1, March 2024
Pages:
7-14
Received:
7 November 2024
Accepted:
29 November 2024
Published:
16 December 2024
Abstract: Background Breast nodules are a health issue that concerns women, and clinical practice entails great concern for accurate diagnosis and appropriate prevention and treatment. This study examined the correlation between ultrasound manifestations and traditional Chinese medicine (TCM) syndrome differentiation of breast nodules. Methods This study included 128 patients with breast nodules based on ultrasound-dependent Breast Imaging-Reporting and Data System (BI-RADS) grading and ultrasound elastography (UE) scoring. This study explored the correlation of syndrome differentiation with age, medical history, nodule size, morphology, boundary status, blood flow signals, BI-RADS grading, and UE score. Results Age and medical history were significantly correlated with TCM syndrome differentiation. Patients with the Chong–Ren imbalance syndrome were older, and those with the phlegm–blood stasis syndrome had the longest disease course. The maximum nodule diameter was not correlated with TCM syndrome differentiation. Furthermore, nodule blood flow signal, BI-RADS grading, and UE scoring were significantly correlated with TCM syndrome differentiation. Patients with the phlegm–blood stasis syndrome had the highest proportion of those with “blood flow signal,” BI-RADS Grade 4, and UE score of four points. Furthermore, the morphology and boundary state of the nodules were not correlated with TCM syndrome differentiation. Conclusion Age, medical history, ultrasound blood flow signals, BI-RADS grading, and UE scoring were correlated with TCM syndrome differentiation in patients with breast nodules, particularly for BI-RADS Grade 4 and UE 4-point nodules, the prevalence of phlegm–blood stasis syndrome is at its highest. After excluding malignant transformation, patients with breast nodules at risk of cancer can receive preventive TCM treatment.
Abstract: Background Breast nodules are a health issue that concerns women, and clinical practice entails great concern for accurate diagnosis and appropriate prevention and treatment. This study examined the correlation between ultrasound manifestations and traditional Chinese medicine (TCM) syndrome differentiation of breast nodules. Methods This study inc...
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,
Jie Zhang
